TB-500

Peptoris Labs

TB-500

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£20.00

Plan your course

Not sure of the dose? Use the figure from this product's research protocol and choose whether it is per day or per week below.

Dose Frequency Course length

vial(s) needed at vial size

Estimate only — based on a steady dose at your chosen frequency and selected vial size. Titration may use less in early weeks. For research use only, not medical advice.

Description

TB-500 is a synthetic version of a naturally occurring 43-amino acid peptide called Thymosin Beta-4, which is found in virtually all human and animal cells. The peptide gained attention in veterinary medicine—particularly horse racing—before becoming one of the most researched compounds for tissue repair. TB-500 works primarily by upregulating actin, a cell-building protein essential for healing and cell migration. Unlike localized treatments, TB-500 has systemic effects, meaning it can promote healing throughout the body regardless of where it's administered. Research suggests it may accelerate recovery from injuries that typically take months to heal, including muscle tears, tendon damage, and ligament sprains.

Quickstart Highlights

TB‑500 is a synthetic peptide fragment corresponding to the active region of thymosin beta‑4 (Tβ4), a naturally occurring 43‑amino‑acid protein involved in tissue repair and regeneration[1][2]

Storage Instructions

Proper storage preserves peptide quality and activity.

  • Lyophilized: Store at −20 °C (−4 °F) in dry, dark conditions; minimize moisture exposure[7].
  • Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F); do not freeze reconstituted solution as freezing can denature peptides.
  • Allow vials to reach room temperature before opening to reduce condensation uptake.
  • Use reconstituted vials within 28 days when stored with bacteriostatic water preservative[8].

How It Works

TB‑500 represents the N‑terminal active fragment of thymosin beta‑4, specifically the heptapeptide sequence Ac‑LKKTETQ[1][2]. This region is responsible for the actin‑binding and cell‑migration properties of the full thymosin molecule. Preclinical studies demonstrate that TB‑500 promotes angiogenesis, accelerates wound healing, and supports tissue regeneration by upregulating cell motility and blood vessel formation[5][6]. Research in animal models shows enhanced collagen deposition and reduced healing time in injury sites treated with thymosin fragments[11]. Recent metabolic studies suggest TB‑500 may act as a prodrug, cleaving to an active pentapeptide metabolite that drives biological activity[12].

Potential Benefits & Side Effects

Observations from preclinical and veterinary literature.

  • Supports accelerated wound healing and tissue repair through enhanced angiogenesis and cell migration[5][6].
  • May reduce inflammation and fibrosis indirectly via thymosin pathways observed in animal models[11].
  • Generally well tolerated in veterinary studies; occasional mild injection‑site reactions (redness, tenderness) reported.
  • Human safety data is limited; no large‑scale clinical trials have been completed for TB‑500 specifically[13].

References

Certificate of Analysis

Every batch of TB-500 is independently lab-tested to a minimum of 98% purity. A Certificate of Analysis is available on request — contact us with your order or lot number and we'll send the COA for your specific batch.

Request a COA

Research Protocol

Full dose-by-dose reconstitution & dosing protocol for TB-500.

View Research Protocol →

For laboratory and scientific research use only. Not medical advice.

For laboratory and research use only. Minimum 98% purity. Supplied in sterile, flip-top headspace vials for laboratory use. Not intended for human or animal consumption, medical, diagnostic, therapeutic or veterinary use. These statements have not been evaluated by the MHRA or FDA. The purchaser accepts full responsibility for safe handling, storage and lawful use.