Glutathione

Peptoris Labs

Glutathione

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£25.00

Plan your course

Not sure of the dose? Use the figure from this product's research protocol and choose whether it is per day or per week below.

Dose Frequency Course length

— vial(s) needed at — vial size

Estimate only — based on a steady dose at your chosen frequency and selected vial size. Titration may use less in early weeks. For research use only, not medical advice.

Description

Glutathione (GSH) is a tripeptide composed of glutamate, cysteine, and glycine, found in virtually every cell in the human body. Often called the 'master antioxidant,' glutathione plays an indispensable role in neutralizing reactive oxygen species, detoxifying xenobiotics and heavy metals, regenerating other antioxidants like vitamins C and E, modulating immune function, and maintaining cellular redox homeostasis. Unlike most antioxidant supplements that work through a single mechanism, glutathione operates through an enzymatic system — glutathione peroxidase, glutathione S-transferase, and glutathione reductase — that provides comprehensive cellular protection. Intracellular glutathione levels decline with age, chronic disease, environmental toxin exposure, and poor nutrition, making it a key biomarker of biological aging and a target for longevity interventions. Research spans decades across thousands of published studies, with clinical investigations into IV glutathione therapy, liposomal glutathione supplementation, and N-acetyl cysteine (NAC) as a glutathione precursor strategy.

 

Quickstart Highlights

Glutathione dosage protocols leverage this master antioxidant tripeptide (γ-L-glutamyl-L-cysteinyl-glycine) to support cellular detoxification, reduce oxidative stress, and maintain redox balance throughout the body[1][2]. As the most abundant intracellular thiol, glutathione plays a central role in neutralizing free radicals, supporting liver function, enhancing immune cell activity, and protecting against environmental toxins[3][4]. 

    Storage Instructions

    Proper storage preserves peptide quality.

    • Lyophilized: Store at −20 °C (−4 °F) in dry, dark conditions; minimize moisture exposure.
    • Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F); use promptly and avoid freeze–thaw.
    • Allow vials to reach room temperature before opening to reduce condensation uptake.
    • Glutathione is relatively unstable once reconstituted—use within 2–3 weeks for optimal potency[6]

    How It Works

    Glutathione (GSH) is the body’s most abundant intracellular antioxidant, present in virtually every cell at concentrations of 1–10 mM[7]. As a tripeptide composed of glutamate, cysteine, and glycine, it functions as the primary thiol-based redox buffer, neutralizing reactive oxygen species (ROS), supporting Phase II detoxification pathways, and facilitating the excretion of xenobiotics and heavy metals[1][8]. The reduced form (GSH) donates electrons to neutralize free radicals and is then recycled back from its oxidized form (GSSG) by glutathione reductase[2]. Clinical and preclinical research demonstrates that maintaining optimal GSH levels supports liver function, immune cell activity, mitochondrial protection, and overall cellular homeostasis[3][9].

    Potential Benefits & Side Effects

    Observations from preclinical and clinical literature.

    • Supports reduction of oxidative stress markers and maintenance of cellular redox balance[1][10].
    • May enhance liver function and support hepatic detoxification pathways[9][11].
    • Research suggests immune-modulating effects, including support for natural killer cell activity and T-cell function[3][12].
    • Clinical studies on skin health indicate potential effects on melanin index and skin brightness with sustained use[13][14].
    • Generally well tolerated; occasional mild injection-site reactions (redness/itch) may occur with subcutaneous administration.
    • Rare reports of gastrointestinal discomfort with high-dose protocols; start with lower doses and titrate gradually.

    References

    Certificate of Analysis

    Every batch of Glutathione is independently lab-tested to a minimum of 98% purity. A Certificate of Analysis is available on request — contact us with your order or lot number and we'll send the COA for your specific batch.

    Request a COA

    Research Protocol

    Full dose-by-dose reconstitution & dosing protocol for Glutathione.

    View Research Protocol →

    For laboratory and scientific research use only. Not medical advice.

    For laboratory and research use only. Minimum 98% purity. Supplied in sterile, flip-top headspace vials for laboratory use. Not intended for human or animal consumption, medical, diagnostic, therapeutic or veterinary use. These statements have not been evaluated by the MHRA or FDA. The purchaser accepts full responsibility for safe handling, storage and lawful use.