GHK-Cu

GHK-Cu is a small peptide naturally found in human plasma that declines significantly with age. It consists of three amino acids (glycine-histidine-lysine) bound to a copper ion, and this copper complex is essential for its biological activity. Originally discovered while studying wound healing, GHK-Cu has since been found to influence the expression of over 4,000 genes—switching many toward a more youthful pattern. In skin, it promotes collagen and elastin synthesis, increases blood vessel formation, and activates regenerative processes. Unlike many anti-aging compounds with questionable evidence, GHK-Cu has substantial research supporting its effects on skin health, wound healing, and tissue regeneration. It's available in both topical skincare formulations and injectable forms, each with different applications and absorption characteristics.